MRP Rs.: 170/-
Packaging: 10x10 Alu Alu
Esomeprazole 40 mg+ Levosulpiride 75 mg SR
It is a proton pump inhibitors that suppresses gastric acid secretion by specific inhibition of the H+/K+ ATPase in the gastric parietal cell.
Gastroesophageal reflux disease. Eradication of Helicobacter pylori in combine with appropriate antibacterial regimens. Healing and maintenance of erosive oesophagitis.
Hypersensitivity to any component of the formulation.
Reduced dose in hepatic insufficiency. Should be taken one hour before meals.
Headache, flatulence, Dry mouth, alkaline phosphatase.
Esomeprazole may interfere with the absorption of drug where gastric PH is an important determinant of bioavailability e.g. ketoconazole, iron salts and digoxin.
Gastroesophageal reflux disease, healing of erosive esophagitis: 20 mg or 40 mg once daily for 4 to 8 weeks. Maintenance of healing of erosive oesophagitis: 20 mg once daily. Symptomatic gastroesophageal reflux: 20 mg once daily for 4 weeks. H-pylori eradication to reduce the risk of duodenal with amoxicillin, 11g twice daily and clarithromycin 500 mg twice daily for 10 days.
Sulpiride is a selective dopamine D2 antagonist having both antipsychotic and antidepressant activity.
In treatment of antidepressant, also used in schizophrenia.
Hypersensitivity, Parkinson’s disease.
Reduced dose is recommended in renal impairment Patients.
Menstrual disorders, amenorrhoea galactorrhea, breast engorgement palpitations, hepatotoxicity.
Adults: Depression: 200 mg- 1000 mg per day. Schizophrenia: 800 mg – 3200 mg per day.